An early, reversible cholesterolgenic etiology of diet-induced insulin resistance

Objective: A buildup of skeletal muscle plasma membrane (PM) cholesterol content in mice occurs within 1 week of a Western-style high-fat diet and causes insulin resistance. The mechanism driving this cholesterol accumulation and insulin resistance is not known. Promising cell data implicate that th...

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Detalles Bibliográficos

Autores principales:	Jacob D. Covert, Brian A. Grice, Matthew G. Thornburg, Manpreet Kaur, Andrew P. Ryan, Lixuan Tackett, Theja Bhamidipati, Natalie D. Stull, Teayoun Kim, Kirk M. Habegger, Donald A. McClain, Joseph T. Brozinick, Jeffrey S. Elmendorf
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2023-06-01
Colección:	Molecular Metabolism
Materias:	Cholesterol Insulin resistance Membrane Skeletal muscle
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2212877823000492
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