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Efficacy of Oroxylin A in ameliorating renal fibrosis with emphasis on Sirt1 activation and TGF-β/Smad3 pathway modulation

IntroductionRenal fibrosis poses a serious threat to human health. At present, there are few types of traditional Chinese medicine used to treat this disease, and Oroxylin A (OA), as a natural product with multiple biological activities, is expected to be used for the treatment of renal fibrosis.Met...

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Hauptverfasser: Guangzhuang Li, Sentao Xian, Xianchao Cheng, Yunhua Hou, Wenqing Jia, Yukui Ma
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-12-01
Schriftenreihe:Frontiers in Pharmacology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1499012/full
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