Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase
The complex regional pain syndrome (CRPS) is characterized by enhanced neurogenic inflammation, mediated by neuropeptides. Neutral endopeptidase (NEP) is a key enzyme in neuropeptide catabolism. We used NEP knock out (ko) mice to investigate whether NEP deficiency leads to increased pain behavior an...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2009-08-01
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| Serie: | Neurobiology of Disease |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S0969996108002805 |
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