The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

Abstract Background Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is associated with reduced quality of life and survival time. Although numero...

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Bibliografische Detailangaben

Hauptverfasser:	Jun Han, Lei Shen, Zheng Zhan, Yuguo Liu, Chang Zhang, Ruochen Guo, Yangjun Luo, Zhiqin Xie, Ying Feng, Guohao Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-03-01
Schriftenreihe:	Nutrition & Metabolism
Schlagworte:	Cancer-associated cachexia Adipose loss MALAT1
Online-Zugang:	https://doi.org/10.1186/s12986-021-00557-0
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