Delimiting the Function of the C-Terminal Extension of the Escherichia coli [NiFe]-Hydrogenase 2 Large Subunit Precursor

The active site of all [NiFe]-hydrogenases (Hyd) has a bimetallic NiFe(CN)2CO cofactor that requires the combined action of several maturation proteins for its biosynthesis and insertion into the precursor form of the large subunit of the enzyme. Cofactor insertion is an intricately controlled proce...

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Hauptverfasser:	Constanze Pinske, Claudia Thomas, Kerstin Nutschan, R. Gary Sawers
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2019-09-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	hydrogenase Hyp proteins large-subunit precursor protein interaction protease maturation
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fmicb.2019.02223/full
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