Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation

Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994. Adopting a structural rigidification approach, a novel series of 3-phenylthiazolo[3,2-a]benzimidazoles 4a–d was designed and synthesised, in an attempt to develop potent anticancer agent that can target...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Ghada H. Al-Ansary, Wagdy M. Eldehna, Hazem A. Ghabbour, Sara T. A. Al-Rashood, Khalid A. Al-Rashood, Radwa A. Eladwy, Abdullah Al-Dhfyan, Maha M. Kabil, Hatem A. Abdel-Aziz
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis Group 2017-01-01
Serie:	Journal of Enzyme Inhibition and Medicinal Chemistry
Ämnen:	Cancer stem cells CD133 cytotoxicity colon cancer benzimidazoles X-ray
Länkar:	http://dx.doi.org/10.1080/14756366.2017.1347166
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!