The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial

Abstract Objectives To investigate the effect of continuous infusion of the potential endothelial cytoprotective agent prostacyclin (Iloprost) 1 ng/kg/min vs. placebo for 72 hours on pulmonary endotheliopathy in mechanically ventilated COVID-19 patients. Trial design A multicenter, randomized (1:1,...

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Detalhes bibliográficos

Principais autores:	Pär Ingemar Johansson, Morten Bestle, Peter Søe-Jensen, Klaus Tjelle Kristiansen, Jakob Stensballe, Niels Erikstrup Clausen, Anders Perner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-08-01
coleção:	Trials
Assuntos:	COVID-19 Randomised controlled trial protocol mechanical ventilation endotheliopathy thrombomodulin
Acesso em linha:	http://link.springer.com/article/10.1186/s13063-020-04696-2
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