Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.
Phosphodiesterases (PDEs) modulate the cellular proliferation involved in the pathophysiology of pulmonary hypertension (PH) by hydrolyzing cAMP and cGMP. The present study was designed to determine whether any of the recently identified PDEs (PDE7-PDE11) contribute to progressive pulmonary vascular...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2011-04-01
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| coleção: | PLoS ONE |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21494592/pdf/?tool=EBI |
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