Spatial multi-omics characterization of neuroblastoma reveals ferroptosis-associated metabolic features in high-risk tumors

Abstract Background Neuroblastoma is a tumor of the sympathetic nervous system and is the most common extracranial solid malignancy in children. It displays striking clinical heterogeneity, ranging from spontaneous regression to a more aggressive, treatment resistant disease. While previous studies...

Полное описание

Библиографические подробности

Главные авторы:	Cui Tu, Chin Wee Tan, James Monkman, Ana Clara Almeida, Gabrielle Antonio-Carreon, Natacha Omer, Giaan Hull, Kimberly Chung, Ahmed M. Mehdi, Antonietta Salerno, Orazio Vittorio, Aaron Mayer, Cleber Machado-Souza, Nanthini Jayabalan, Yi-Chin Toh, Hui Nee Hon, Fernanda de Almeida Brehm Pinhatti, Selene Elifio-Esposito, Wayne Nicholls, Lucia de Noronha, Arutha Kulasinghe, Fernando Souza-Fonseca-Guimaraes
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-03-01
Серии:	Genome Medicine
Предметы:	Neuroblastoma Multi-omics Ferroptosis Tumor microenvironment
Online-ссылка:	https://doi.org/10.1186/s13073-026-01622-0
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!