Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines

We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents. This method includes a Lewis acid-catalyzed opening of the donor–acceptor cyclopropane with pr...

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Bibliographic Details

Main Authors:	Maksim A. Boichenko, Andrey Yu. Plodukhin, Vitaly V. Shorokhov, Danyla S. Lebedev, Anastasya V. Filippova, Sergey S. Zhokhov, Elena A. Tarasenko, Victor B. Rybakov, Igor V. Trushkov, Olga A. Ivanova
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2022-12-01
Series:	Molecules
Subjects:	donor–acceptor cyclopropanes primary amines pyrrolidin-2-ones benz[<i>g</i>]indolizidines
Online Access:	https://www.mdpi.com/1420-3049/27/23/8468
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