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Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines

We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents. This method includes a Lewis acid-catalyzed opening of the donor–acceptor cyclopropane with pr...

Deskribapen osoa

Gorde:
Egile Nagusiak: Maksim A. Boichenko, Andrey Yu. Plodukhin, Vitaly V. Shorokhov, Danyla S. Lebedev, Anastasya V. Filippova, Sergey S. Zhokhov, Elena A. Tarasenko, Victor B. Rybakov, Igor V. Trushkov, Olga A. Ivanova
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2022-12-01
Saila:Molecules
Gaiak:
donor–acceptor cyclopropanes
primary amines
pyrrolidin-2-ones
benz[<i>g</i>]indolizidines
Sarrera elektronikoa:https://www.mdpi.com/1420-3049/27/23/8468
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