Outcomes of patients with CLL and borderline IGHV mutational status: a systematic review and meta analysis

Abstract The immunoglobulin heavy chain variable region (IGHV) mutational status is a major prognostic factor in chronic lymphocytic leukemia (CLL). While patients are conventionally classified as mutated (M-IGHV) or unmutated (U-IGHV) using a 98% germline identity cutoff, increasing interest has fo...

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Detalhes bibliográficos

Principais autores:	Francesco Angotzi, Arianna Bevilacqua, Andrea Serafin, Nicolò Danesin, Alessandro Cellini, Giovanni Leone, Mattia D’Antiga, Elisa Pagnin, Federica Frezzato, Monica Facco, Francesco Piazza, Livio Trentin, Andrea Visentin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
Colecção:	Biomarker Research
Assuntos:	Chronic lymphocytic leukemia IGHV mutational status Immunogenetic Prognostic factors
Acesso em linha:	https://doi.org/10.1186/s40364-026-00913-3
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