The relative immunogenicity of 20-valent and 15-valent pneumococcal conjugate vaccines: A systematic review and network meta-analysis

Higher-valent pneumococcal conjugate vaccines (PCV) may reduce adult pneumococcal disease, but no head-to-head trials compare PCV20 vs. PCV15 in adults. We synthesized serotype-specific immunogenicity from randomized controlled trials using a network meta-analysis via the common comparator PCV13. Pu...

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Detalhes bibliográficos

Principais autores:	Ilaria Valentini, Erika Alessandra Strangi, Gaia Baccarini, Claudia Martini, Monica Paoloni, Alice Mannocci, Chiara de Waure
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2026-12-01
coleção:	Human Vaccines & Immunotherapeutics
Assuntos:	Pneumococcal conjugate vaccine PCV20 PCV15 adults network meta-analysis immunogenicity
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/21645515.2026.2702726
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