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Can a Proper T-Cell Development Occur in an Altered Thymic Epithelium? Lessons From EphB-Deficient Thymi

For a long time, the effects of distinct Eph tyrosine kinase receptors and their ligands, ephrins on the structure, immunophenotype, and development of thymus and their main cell components, thymocytes (T) and thymic epithelial cells (TECs), have been studied. In recent years, the thymic phenotype o...

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Principais autores: Juan José Muñoz, Javier García-Ceca, Sara Montero-Herradón, Beatriz Sánchez del Collado, David Alfaro, Agustín Zapata
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Endocrinology
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Acceso en liña:http://journal.frontiersin.org/article/10.3389/fendo.2018.00135/full
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