Targeting cGAS-STING-macrophage axis: a novel therapeutic horizon for renal fibrosis

Renal fibrosis, a pivotal pathological hallmark of chronic kidney disease (CKD), arises from persistent inflammatory responses and extracellular matrix (ECM) deposition. Emerging evidence indicates the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway has exerted...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Qi Wei, Kui Zhao, Fuyun Jia, Jing Zhou, Tianrui Liu, Shengwei Gao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-04-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	cGAS-STING inflammation macrophages renal fibrosis targeted therapy
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1809851/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!