FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo.
BACKGROUND: The molecular mechanisms that are involved in the growth and invasiveness of osteosarcoma, an aggressive and invasive primary bone tumor, are not fully understood. The transcriptional co-factor FHL2 (four and a half LIM domains protein 2) acts as an oncoprotein or as a tumor suppressor d...
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| Huvudupphov: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Public Library of Science (PLoS)
2013-01-01
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| Serie: | PLoS ONE |
| Länkar: | http://europepmc.org/articles/PMC3557236?pdf=render |
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