The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts*

The Niemann-Pick C1 (NPC1) protein regulates the transport of cholesterol from late endosomes/lysosomes to other compartments responsible for maintaining intracellular cholesterol homeostasis. The present study examined the expression of the NPC1 gene and the distribution of the NPC1 protein that re...

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Үндсэн зохиолчид:	William S. Garver, David Jelinek, Gordon A. Francis, Bruce D. Murphy
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2008-05-01
Цуврал:	Journal of Lipid Research
Нөхцлүүд:	cholesterol homeostasis coated-pit pathway late endosomes/lysosomes low density lipoprotein-derived cholesterol sterol-regulatory element binding protein
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0022227520425969
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!