Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2

Abstract Originally discovered in the circulation of pregnant women as a protein secreted by placental trophoblasts, the metalloprotease pregnancy-associated plasma protein A (PAPP-A) is also widely expressed by many other tissues. It cleaves insulin-like growth factor-binding proteins (IGFBPs) to i...

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المؤلفون الرئيسيون:	Qihang Zhong, Honglei Chu, Guopeng Wang, Cheng Zhang, Rong Li, Fusheng Guo, Xinlu Meng, Xiaoguang Lei, Youli Zhou, Ruobing Ren, Lin Tao, Ningning Li, Ning Gao, Yuan Wei, Jie Qiao, Jing Hang
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Nature Publishing Group 2022-12-01
سلاسل:	Cell Discovery
الوصول للمادة أونلاين:	https://doi.org/10.1038/s41421-022-00502-2
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!