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The pro-atherogenic enzyme PAPP-A is active in eluates from human carotid and femoral atherosclerotic plaques

Background: Pregnancy-associated plasma protein-A (PAPP-A) regulates bioavailability of insulin-like growth factor 1 (IGF1) in various tissues by proteolytic cleavage of a subset of IGF-binding proteins (IGFBPs). Pre-clinical studies have established a role of PAPP-A in atherosclerosis and proposed...

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Detaylı Bibliyografya
Asıl Yazarlar: Mette Faurholdt Gude, Rikke Hjortebjerg, Mette Bjerre, Anne Kathrine Nissen Pedersen, Claus Oxvig, Lars Melholt Rasmussen, Jan Frystyk, Lasse Steffensen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-09-01
Seri Bilgileri:Atherosclerosis Plus
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2667089524000415
Etiketler: Etiketle
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