A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling

In this study, we examined the effect of the GP130-targeting molecule, LMT-28, on lipopolysaccharide- (LPS-) induced bone resorption around implants in diabetic models using in vitro and rat animal experiments. First, LMT-28 was added to osteoblasts stimulated by LPS and advanced glycation end produ...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Qi-qi Liu, Wei-wei Wu, Jian Yang, Rui-bin Wang, Ling-ling Yuan, Pei-zhao Peng, Mao-yun Zeng, Ke Yu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Wiley 2023-01-01
Σειρά:	Mediators of Inflammation
Διαθέσιμο Online:	http://dx.doi.org/10.1155/2023/9330439
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