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SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity

Sterile alpha motif and histidine-aspartic acid domain-containing protein 1 (SAMHD1) is a deoxynucleotide triphosphate (dNTP) hydrolase that plays an important role in the homeostatic balance of cellular dNTPs. Its emerging role as an effector of innate immunity is affirmed by mutations in the SAMHD...

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Detalles Bibliográficos
Principais autores: Christopher H. Mauney, Thomas Hollis
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2018-04-01
Series:Autoimmunity
Assuntos:
Acceso en liña:http://dx.doi.org/10.1080/08916934.2018.1454912
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