Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine-derived SIX2-positive renal progenitor cell line

Abstract Background CKD affects approximately 850 million people worldwide and is a leading cause of mortality. Podocytes, cells in the kidney are terminally differentiated and incapable of division in vivo making the establishment of primary cultures particularly challenging. The ability of cells t...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Chantelle Thimm, Rosanne Mack, Osmond Adjei-Aruna, Wasco Wruck, Dalvir Kular, Ania Koziell, Kate Bramham, James Adjaye
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2025-11-01
سلاسل:	Stem Cell Research & Therapy
الموضوعات:	Partial reprogramming Rejuvenation Nephrogenesis Interferon-γ Baricitinib JAK/STAT signaling pathway
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13287-025-04710-x
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!