Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Abstract Centrioles define centrosome structure and function. Deregulation of centriole numbers can cause developmental defects and cancer. The p53 tumor suppressor limits the growth of cells lacking or harboring additional centrosomes and can be engaged by the “mitotic surveillance” or the “PIDDoso...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2024-10-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-024-53222-4 |
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