Nicorandil prevents sirolimus-induced production of reactive oxygen species, endothelial dysfunction, and thrombus formation

Sirolimus (SRL) is widely used to prevent restenosis after percutaneous coronary intervention. However, its beneficial effect is hampered by complications of thrombosis. Several studies imply that reactive oxygen species (ROS) play a critical role in endothelial dysfunction and thrombus formation. T...

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Hlavní autoři:	Ken Aizawa, Youko Takahari, Naoko Higashijima, Kenichi Serizawa, Kenji Yogo, Nobuhiko Ishizuka, Koichi Endo, Naoto Fukuyama, Katsuya Hirano, Hideyuki Ishida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2015-03-01
Edice:	Journal of Pharmacological Sciences
Témata:	Nicorandil Sirolimus Thrombosis Reactive oxygen species Endothelial cells
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1347861315000341
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