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Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.

BACKGROUND: An antianginal K(ATP) channel opener nicorandil has various beneficial effects on cardiovascular systems; however, its effects on pulmonary vasculature under pulmonary arterial hypertension (PAH) have not yet been elucidated. Therefore, we attempted to determine whether nicorandil can at...

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Bibliografische Detailangaben
Hauptverfasser: Makoto Sahara, Masataka Sata, Toshihiro Morita, Yasunobu Hirata, Ryozo Nagai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3316574?pdf=render
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