Phase Separation Competent TIA1 Couples Glycolytic Shutdown to CD8<sup>+</sup> T-Cell Activation and Shapes the Efficacy of Intravesical BCG in Bladder Cancer
Metabolic immune evasion is a major factor limiting the long-term efficacy of intravesical Bacillus Calmette–Guérin (BCG) therapy in non-muscle-invasive bladder cancer (NMIBC). TIA1 is a stress granule RNA-binding protein with liquid–liquid phase separation (LLPS) capacity. Its role in tumor metabol...
I tiakina i:
| Ngā kaituhi matua: | , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
MDPI AG
2025-11-01
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| Rangatū: | Biology |
| Ngā marau: | |
| Urunga tuihono: | https://www.mdpi.com/2079-7737/14/11/1576 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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