Dysfunctional mitochondria trap proteins in the intermembrane space
Abstract The accumulation of mitochondrial precursor proteins in the cytosol due to mitochondrial dysfunction compromises cellular proteostasis and is a hallmark of diseases. Why non-imported precursors are toxic and how eukaryotic cells prevent their accumulation in the cytosol is still poorly unde...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Springer Nature
2025-06-01
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| Cyfres: | The EMBO Journal |
| Pynciau: | |
| Mynediad Ar-lein: | https://doi.org/10.1038/s44318-025-00486-1 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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