Expression of Mutant Glycine Receptors in <i>Xenopus</i> Oocytes Using Canonical and Non-Canonical Amino Acids Reveals Distinct Roles of Conserved Proline Residues

Pentameric ligand-gated ion channels (pLGIC) play important roles in fast neuronal signal transmission. Functional receptors are pentamers, with each subunit having an extracellular domain (ECD), a transmembrane domain (TMD) and an intracellular domain. The binding of the agonist to the ECD induces...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Sarah C. R. Lummis, Dennis A. Dougherty
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2022-10-01
Serier:	Membranes
Fag:	ligand-gated ion channel Cys-loop receptor cis prolyl peptide bond noncanonical amino acid mutagenesis electrophysiology
Online adgang:	https://www.mdpi.com/2077-0375/12/10/1012
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!