Evolution of mutations in the ftsI gene leading to amino acid substitutions in PBP3 in Haemophilus influenzae strains under the selective pressure of ampicillin and cefuroxime
Background: Aminopenicillins are recommended agents for non-invasive Haemophilus influenzae infections. One of the mechanisms of resistance to β-lactams is the alteration of the transpeptidase region of penicillin binding protein 3 (PBP3) which is caused by mutations in the ftsI gene. It was shown t...
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| Principais autores: | , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Elsevier
2024-09-01
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| 丛编: | International Journal of Medical Microbiology |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S1438422124000304 |
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