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HNEAP Regulates Necroptosis of Cardiomyocytes by Suppressing the m5C Methylation of Atf7 mRNA

Abstract PIWI‐interacting RNAs (piRNAs) are highly expressed in various cardiovascular diseases. However, their role in cardiomyocyte death caused by ischemia/reperfusion (I/R) injury, especially necroptosis, remains elusive. In this study, a heart necroptosis‐associated piRNA (HNEAP) is found that...

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Hoofdauteurs: Kai Wang, Fu‐Hai Li, Lu‐Yu Zhou, Xue‐Mei Zhao, Xiang‐Qian Gao, Cui‐Yun Liu, Xin‐Min Li, Xin‐Zhe Chen, Yan Zhao, Xue‐Li Cheng, Rui‐Quan Wang, Rui‐Feng Li, Yu‐Hui Zhang, Fei Gao, Jin‐Wei Tian, Kun Wang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2023-12-01
Reeks:Advanced Science
Onderwerpen:
ATF7
cardiomyocyte necroptosis
CHMP2A
HNEAP
m5C methylation
Online toegang:https://doi.org/10.1002/advs.202304329
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