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Genetic alterations of C9orf72, SOD1, TARDBP, FUS, and UBQLN2 genes in patients with Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis is the most common motor neuron disease of the adulthood. Genetic analyses performed on cases with sporadic ALS (sALS) and familial ALS (fALS) have revealed mutations most commonly in the genes C9orf72, SOD1, TARDBP, FUS, and UBQLN2. The aim of this study was to investi...

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Principais autores: Ciftci Vildan, Darbas Sule, Bilgen Turker, Uysal Hilmi, Karauzum Berker Sibel
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2019-01-01
Serier:Cogent Medicine
Fag:
als
c9orf72
sod1
tardbp
fus
ubqln2
Online adgang:http://dx.doi.org/10.1080/2331205X.2019.1582400
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