WN1703 alleviates gout symptoms via inflammatory signaling pathways in an acute gout rat model

We previously synthesized the xanthine oxidoreductase (XOR) inhibitor WN1703. In addition to showing XOR inhibitory effects, WN1703 also showed anti-inflammatory effects in a rat hyperuricemia model. Here, we studied WN1703's anti-inflammatory effects on gout and explored the underlying mechanisms....

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Bibliografische Detailangaben

Hauptverfasser:	Fuyao Liu, Xiaodan Lu, Lei Zhang, Jing Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-12-01
Schriftenreihe:	Pharmaceutical Science Advances
Schlagworte:	Hyperuricemia Acute gouty arthritis Xanthine oxidoreductase inhibitors Anti-inflammation
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2773216924000059
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