WN1703 alleviates gout symptoms via inflammatory signaling pathways in an acute gout rat model

We previously synthesized the xanthine oxidoreductase (XOR) inhibitor WN1703. In addition to showing XOR inhibitory effects, WN1703 also showed anti-inflammatory effects in a rat hyperuricemia model. Here, we studied WN1703's anti-inflammatory effects on gout and explored the underlying mechanisms....

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Fuyao Liu, Xiaodan Lu, Lei Zhang, Jing Li
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2024-12-01
Cyfres:	Pharmaceutical Science Advances
Pynciau:	Hyperuricemia Acute gouty arthritis Xanthine oxidoreductase inhibitors Anti-inflammation
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2773216924000059
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!