Hepcidin and Anemia: A Tight Relationship
Hepcidin, the master regulator of systemic iron homeostasis, tightly influences erythrocyte production. High hepcidin levels block intestinal iron absorption and macrophage iron recycling, causing iron restricted erythropoiesis and anemia. Low hepcidin levels favor bone marrow iron supply for hemogl...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2019-10-01
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| Colección: | Frontiers in Physiology |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/article/10.3389/fphys.2019.01294/full |
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