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Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt

Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3), thereby offering survival signaling. While the epit...

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Autors principals: Niit Maximilian, Hoskin Victoria, Carefoot Esther, Geletu Mulu, Arulanandam Rozanne, Elliott Bruce, Raptis Leda
Format: Artigo
Idioma:Inglês
Publicat: De Gruyter 2015-12-01
Col·lecció:Biomolecular Concepts
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Accés en línia:https://doi.org/10.1515/bmc-2015-0022
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