S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis

Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins S100A8/A9 locally released by the synovium during...

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主要な著者:	Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie, Giuliana Ascone, Fons van de Loo, Marije Koenders, Peter van der Kraan, Annet Sloetjes, Thomas Vogl, Johannes Roth, Edwin J. W. Geven, Arjen B. Blom, Peter L. E. M. van Lent
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2017-09-01
シリーズ:	Arthritis Research & Therapy
主題:	S100 Mobilization Ly6C high/low monocytes Systemic effects Collagenase-induced osteoarthritis
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13075-017-1426-6
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