Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are needed for biological activity. Similarly, neuropeptide pre...

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Váldodahkkit:	Jeanette Zanker, Daniela Hüser, Adrien Savy, Sara Lázaro-Petri, Eva-Maria Hammer, Christoph Schwarzer, Regine Heilbronn
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2023-11-01
Ráidu:	Frontiers in Molecular Neuroscience
Fáttát:	adeno-associated virus gene therapy neuropeptide SH-SY5Y differentiation
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1280556/full
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