Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are needed for biological activity. Similarly, neuropeptide pre...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Jeanette Zanker, Daniela Hüser, Adrien Savy, Sara Lázaro-Petri, Eva-Maria Hammer, Christoph Schwarzer, Regine Heilbronn
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2023-11-01
سلاسل:	Frontiers in Molecular Neuroscience
الموضوعات:	adeno-associated virus gene therapy neuropeptide SH-SY5Y differentiation
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1280556/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!