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Tyrosine Kinases as Druggable Targets in Cancer

Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL...

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Bibliographic Details
Corporate Author: Ren, Huan
Format: Livro
Language:Inglês
Published: IntechOpen 2019
Subjects:
Online Access:https://directory.doabooks.org/handle/20.500.12854/67013
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