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The Role of G-protein Coupled Receptor Proteolytic Site (GPS) Cleavage in Polycystin-1 Biogenesis, Trafficking and Function
Polycystin-1 (PC1) is encoded by PKD1, the principal gene mutated in autosomal dominant polycystic kidney disease (ADPKD). The protein regulates terminal differentiation of tubular structures in the kidney and is required to maintain their structural integrity. A fundamental property of PC1 is post-...
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| Format: | Livro |
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| Langue: | Inglês |
| Publié: |
Exon Publications
2015-11-18
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| Sujets: | |
| Accès en ligne: | https://directory.doabooks.org/handle/20.500.12854/136657 |
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