Hypothesis: ceramide conditionally activates atypical protein kinases C, Raf-1 and KSR through binding to their cysteine-rich domains.

Bằng van Blitterswijk, W J
Được phát hành 1998

Rapid attenuation of receptor-induced diacylglycerol and phosphatidic acid by phospholipase D-mediated transphosphatidylation: formation of bisphosphatidic acid.

Bằng van Blitterswijk, W J, Hilkmann, H
Được phát hành 1993

Specificity of cysteine-rich domains in diacylglycerol kinases and protein kinases C.

Bằng Houssa, B, van Blitterswijk, W J
Được phát hành 1998

Consensus sequences for ATP-binding sites in protein kinases do not apply to diacylglycerol kinases.

Bằng Schaap, D, van der Wal, J, van Blitterswijk, W J
Được phát hành 1994

Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C...

Bằng van Dijk, M C, Hilkmann, H, van Blitterswijk, W J
Được phát hành 1997

Changes in concanavalin A-mediated agglutination of hormone-dependent mouse mammary tumour cells during serial transplantation.

Bằng Sluyser, M., van der Valk, M., van Blitterswijk, W. J.
Được phát hành 1980

N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx

Bằng Veldman, R J, Zerp, S, van Blitterswijk, W J, Verheij, M
Được phát hành 2004

Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids.

Bằng Limatola, C, Schaap, D, Moolenaar, W H, van Blitterswijk, W J
Được phát hành 1994

Membrane fluidity, capping of cell-surface antigens and immune response in mouse leukaemia cells.

Bằng Hilgers, J., van der Sluis, P. J., van Blitterswijk, W. J., Emmelot, P.
Được phát hành 1978

Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries.

Bằng Walker, A J, Draeger, A, Houssa, B, van Blitterswijk , W J, Ohanian, V, Ohanian, J
Được phát hành 2001

Protein kinase C activation by acidic proteins including 14-3-3.

Bằng Van Der Hoeven, P C, Van Der Wal, J C, Ruurs, P, Van Blitterswijk, W J
Được phát hành 2000

Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.

Bằng Schaap, D, van der Wal, J, van Blitterswijk, W J, van der Bend, R L, Ploegh, H L
Được phát hành 1993

The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Comparison with the response to...

Bằng van der Bend, R L, de Widt, J, van Corven, E J, Moolenaar, W H, van Blitterswijk, W J
Được phát hành 1992

Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.

Bằng van der Bend, R L, Brunner, J, Jalink, K, van Corven, E J, Moolenaar, W H, van Blitterswijk, W J
Được phát hành 1992

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin.

Bằng van Corven, E J, van Rijswijk, A, Jalink, K, van der Bend, R L, van Blitterswijk, W J, Moolenaar, W H
Được phát hành 1992

Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: depen...

Bằng van Dijk, M, Muriana, F J, van Der Hoeven, P C, de Widt, J, Schaap, D, Moolenaar, W H, van Blitterswijk, W J
Được phát hành 1997

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis.

Bằng Jalink, K, Hengeveld, T, Mulder, S, Postma, F R, Simon, M F, Chap, H, van der Marel, G A, van Boom, J H, van Blitterswijk, W J, Moolenaar, W H
Được phát hành 1995