Site-Specific Tandem Knoevenagel Condensation–Michael Addition To Generate Antibody–Drug Conjugates

Por Kudirka, Romas A., Barfield, Robyn M., McFarland, Jesse M., Drake, Penelope M., Carlson, Adam, Bañas, Stefanie, Zmolek, Wes, Garofalo, Albert W., Rabuka, David
Publicado no ACS Med Chem Lett (2016)

Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes

Por Drake, Penelope M., Albers, Aaron E., Baker, Jeanne, Banas, Stefanie, Barfield, Robyn M., Bhat, Abhijit S., de Hart, Gregory W., Garofalo, Albert W., Holder, Patrick, Jones, Lesley C., Kudirka, Romas, McFarland, Jesse, Zmolek, Wes, Rabuka, David
Publicado no Bioconjug Chem (2014)