Biophysical Studies on Interactions and Assembly of Full-size E3 Ubiquitin Ligase: SUPPRESSOR OF CYTOKINE SIGNALING 2 (SOCS2)-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 (RBX2)

gan Bulatov, Emil, Martin, Esther M., Chatterjee, Sneha, Knebel, Axel, Shimamura, Satoko, Konijnenberg, Albert, Johnson, Clare, Zinn, Nico, Grandi, Paola, Sobott, Frank, Ciulli, Alessio
Cyhoeddwyd yn J Biol Chem (2015)

Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons

gan Ramsden, Nigel, Perrin, Jessica, Ren, Zhao, Lee, Byoung Dae, Zinn, Nico, Dawson, Valina L., Tam, Danny, Bova, Michael, Delling, Manja, Drewes, Gerard, Bantscheff, Marcus, Bard, Frederique, Dawson, Ted M., Hopf, Carsten
Cyhoeddwyd 2011

Systematic analysis of protein turnover in primary cells

gan Mathieson, Toby, Franken, Holger, Kosinski, Jan, Kurzawa, Nils, Zinn, Nico, Sweetman, Gavain, Poeckel, Daniel, Ratnu, Vikram S., Schramm, Maike, Becher, Isabelle, Steidel, Michael, Noh, Kyung-Min, Bergamini, Giovanna, Beck, Martin, Bantscheff, Marcus, Savitski, Mikhail M.
Cyhoeddwyd yn Nat Commun (2018)

CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model

gan Cansfield, Andrew D., Ladduwahetty, Tammy, Sunose, Mihiro, Ellard, Katie, Lynch, Rosemary, Newton, Anthea L., Lewis, Ann, Bennett, Gavin, Zinn, Nico, Thomson, Douglas W., Rüger, Anne J., Feutrill, John T., Rausch, Oliver, Watt, Alan P., Bergamini, Giovanna
Cyhoeddwyd yn ACS Med Chem Lett (2016)

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

gan Thomson, Douglas W., Poeckel, Daniel, Zinn, Nico, Rau, Christina, Strohmer, Katrin, Wagner, Anne J., Graves, Alan P., Perrin, Jessica, Bantscheff, Marcus, Duempelfeld, Birgit, Kasparcova, Viera, Ramanjulu, Joshi M., Pesiridis, G. Scott, Muelbaier, Marcel, Bergamini, Giovanna
Cyhoeddwyd yn ACS Med Chem Lett (2019)

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices

gan Khan, Muzamil Majid, Poeckel, Daniel, Halavatyi, Aliaksandr, Zukowska-Kasprzyk, Joanna, Stein, Frank, Vappiani, Johanna, Sevin, Daniel C., Tischer, Christian, Zinn, Nico, Eley, Jessica D., Gudmann, Natasja Stæhr, Muley, Thomas, Winter, Hauke, Fisher, Andrew J., Nanthakumar, Carmel B., Bergamini, Giovanna, Pepperkok, Rainer
Cyhoeddwyd yn Eur Respir J (2021)

Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS

gan Schenck Eidam, Hilary, Russell, John, Raha, Kaushik, DeMartino, Michael, Qin, Donghui, Guan, Huiping Amy, Zhang, Zhiliu, Zhen, Gong, Yu, Haiyu, Wu, Chengde, Pan, Yan, Joberty, Gerard, Zinn, Nico, Laquerre, Sylvie, Robinson, Sharon, White, Angela, Giddings, Amanda, Mohammadi, Ehsan, Greenwood-Van Meerveld, Beverly, Oliff, Allen, Kumar, Sanjay, Cheung, Mui
Cyhoeddwyd yn ACS Med Chem Lett (2018)

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

gan Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus
Cyhoeddwyd yn Cell (2018)

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

gan Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.
Cyhoeddwyd yn Nat Commun (2019)

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

gan Mares, Alina, Miah, Afjal H., Smith, Ian E. D., Rackham, Mark, Thawani, Aditya R., Cryan, Jenni, Haile, Pamela A., Votta, Bartholomew J., Beal, Allison M., Capriotti, Carol, Reilly, Michael A., Fisher, Don T., Zinn, Nico, Bantscheff, Marcus, MacDonald, Thomas T., Vossenkamper, Anna, Dace, Phoebe, Churcher, Ian, Benowitz, Andrew B., Watt, Gillian, Denyer, Jane, Scott-Stevens, Paul, Harling, John D.
Cyhoeddwyd yn Commun Biol (2020)

Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

gan Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.
Cyhoeddwyd yn Nat Commun (2020)

Catalytic in vivo protein knockdown by small-molecule PROTACs

gan Bondeson, Daniel P, Mares, Alina, Smith, Ian E D, Ko, Eunhwa, Campos, Sebastien, Miah, Afjal H, Mulholland, Katie E, Routly, Natasha, Buckley, Dennis L, Gustafson, Jeffrey L, Zinn, Nico, Grandi, Paola, Shimamura, Satoko, Bergamini, Giovanna, Faelth-Savitski, Maria, Bantscheff, Marcus, Cox, Carly, Gordon, Deborah A, Willard, Ryan R, Flanagan, John J, Casillas, Linda N, Votta, Bartholomew J, den Besten, Willem, Famm, Kristoffer, Kruidenier, Laurens, Carter, Paul S, Harling, John D, Churcher, Ian, Crews, Craig M
Cyhoeddwyd yn Nat Chem Biol (2015)