A Phase I and pharmacodynamic study of AT9283, a small molecule inhibitor of aurora kinases in patients with relapsed/refractory leukemia or myelofibrosis

per Foran, James, Ravandi, Farhad, Wierda, William, Garcia-Manero, Guillermo, Verstovsek, Srdan, Kadia, Tapan, Burger, Jan, Yule, Murray, Langford, Gillian, Lyons, John, Ayrton, John, Lock, Victoria, Borthakur, Gautham, Cortes, Jorge, Kantarjian, Hagop
Publicat 2013

AT7519, A NOVEL SMALL MOLECULE MULTI-CYCLIN DEPENDENT KINASE INHIBITOR, INDUCES APOPTOSIS IN MULTIPLE MYELOMA VIA GSK-3β ACTIVATION AND RNA POLYMERASE II INHIBITION

per Santo, Loredana, Vallet, Sonia, Hideshima, Teru, Cirstea, Diana, Ikeda, Hiroshi, Pozzi, Samantha, Patel, Kishan, Okawa, Yutaka, Gorgun, Gullu, Perrone, Giulia, Calabrese, Elisabetta, Yule, Murray, Squires, Matt, Ladetto, Marco, Boccadoro, Mario, Richardson, Paul G, Munshi, Nikhil C., Anderson, Kenneth C., Raje, Noopur
Publicat 2010