Human primary immunodeficiency caused by expression of a kinase-dead p110δ mutant

por Cohen, Sarah Beaussant, Bainter, Wayne, Johnson, Jared L., Lin, Ting-Yu, Wong, Jenny C.Y., Wallace, Jacqueline, Jones, Jennifer, Mir, Fatima, Qamar, Farah, Cantley, Lewis C., Geha, Raif S., Chou, Janet
Publicado en J Allergy Clin Immunol (2018)

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

por Mullarky, Edouard, Lucki, Natasha C., Beheshti Zavareh, Reza, Anglin, Justin L., Gomes, Ana P., Nicolay, Brandon N., Wong, Jenny C. Y., Christen, Stefan, Takahashi, Hidenori, Singh, Pradeep K., Blenis, John, Warren, J. David, Fendt, Sarah-Maria, Asara, John M., DeNicola, Gina M., Lyssiotis, Costas A., Lairson, Luke L., Cantley, Lewis C.
Publicado en Proc Natl Acad Sci U S A (2016)

Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy

por Lundquist, Mark R., Goncalves, Marcus D., Loughran, Ryan M., Possik, Elite, Vijayaraghavan, Tarika, Yang, Annan, Pauli, Chantal, Ravi, Archna, Verma, Akanksha, Yang, Zhiwei, Johnson, Jared L., Wong, Jenny C.Y., Ma, Yilun, Hwang, Katie Seo-Kyoung, Weinkove, David, Divecha, Nullin, Asara, John M., Elemento, Olivier, Rubin, Mark A., Kimmelman, Alec C., Pause, Arnim, Cantley, Lewis C., Emerling, Brooke M.
Publicado en Mol Cell (2018)