Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer’s Disease

Por Lai, Robert Y. K., Harrington, Charles R., Wischik, Claude M.
Publicado no Biomolecules (2016)

Erratum: Lai, R.Y.K.; Harrington, C.R.; Wischik, C.M. Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer’s Disease. Biomolecules 2016, 6, 19

Por Lai, Robert Y. K., Harrington, Charles R., Wischik, Claude M.
Publicado no Biomolecules (2016)

Modeling Prion-Like Processing of Tau Protein in Alzheimer’s Disease for Pharmaceutical Development

Por Wischik, Claude M., Schelter, Björn O., Wischik, Damon J., Storey, John M. D., Harrington, Charles R.
Publicado no J Alzheimers Dis (2018)

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

Por Šimić, Goran, Babić Leko, Mirjana, Wray, Selina, Harrington, Charles, Delalle, Ivana, Jovanov-Milošević, Nataša, Bažadona, Danira, Buée, Luc, de Silva, Rohan, Di Giovanni, Giuseppe, Wischik, Claude, Hof, Patrick R.
Publicado no Biomolecules (2016)

Monoaminergic Neuropathology in Alzheimer's disease

Por Šimić, Goran, Leko, Mirjana Babić, Wray, Selina, Harrington, Charles, Delalle, Ivana, Jovanov-Milošević, Nataša, Bažadona, Danira, Buée, Luc, de Silva, Rohan, Di Giovanni, Giuseppe, Wischik, Claude, Hof, Patrick R.
Publicado no Prog Neurobiol (2016)

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

Por Flores-Rodríguez, Paola, Ontiveros-Torres, Miguel A., Cárdenas-Aguayo, María C., Luna-Arias, Juan P., Meraz-Ríos, Marco A., Viramontes-Pintos, Amparo, Harrington, Charles R., Wischik, Claude M., Mena, Raúl, Florán-Garduño, Benjamin, Luna-Muñoz, José
Publicado no Front Neurosci (2015)

Staging of Cytoskeletal and β-Amyloid Changes in Human Isocortex Reveals Biphasic Synaptic Protein Response during Progression of Alzheimer’s Disease

Por Mukaetova-Ladinska, Elizabeta B., Garcia-Siera, Francisco, Hurt, Jenny, Gertz, Herman J., Xuereb, John H., Hills, Richard, Brayne, Carol, Huppert, Felicia A., Paykel, Eugene S., McGee, Magnus, Jakes, Ross, G. Honer, William, Harrington, Charles R., Wischik, Claude M.
Publicado em 2000

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

Por Schwab, Karima, Frahm, Silke, Horsley, David, Rickard, Janet E., Melis, Valeria, Goatman, Elizabeth A., Magbagbeolu, Mandy, Douglas, Morag, Leith, Michael G., Baddeley, Thomas C., Storey, John M. D., Riedel, Gernot, Wischik, Claude M., Harrington, Charles R., Theuring, Franz
Publicado no Front Mol Neurosci (2018)

Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease

Por Harrington, Charles R., Storey, John M. D., Clunas, Scott, Harrington, Kathleen A., Horsley, David, Ishaq, Ahtsham, Kemp, Steven J., Larch, Christopher P., Marshall, Colin, Nicoll, Sarah L., Rickard, Janet E., Simpson, Michael, Sinclair, James P., Storey, Lynda J., Wischik, Claude M.
Publicado no J Biol Chem (2015)

Lewy Body Variant of Alzheimer's Disease: Selective Neocortical Loss of t-SNARE Proteins and Loss of MAP2 and α-Synuclein in Medial Temporal Lobe

Por Mukaetova-Ladinska, Elizabeta B., Xuereb, John H., Garcia-Sierra, Francisco, Hurt, Jenny, Gertz, Herman-J., Hills, Richard, Brayne, Carol, Huppert, Felicia A., Paykel, Eugene S., McGee, Magnus A., Jakes, Ross, Honer, William G., Harrington, Charles R., Wischik, Claude M., CC75C Collaboration Group
Publicado no ScientificWorldJournal (2009)

Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models

Por Melis, Valeria, Magbagbeolu, Mandy, Rickard, Janet E., Horsley, David, Davidson, Kathleen, Harrington, Kathleen A., Goatman, Keith, Goatman, Elizabeth A., Deiana, Serena, Close, Steve P., Zabke, Claudia, Stamer, Karsten, Dietze, Silke, Schwab, Karima, Storey, John M.D., Harrington, Charles R., Wischik, Claude M., Theuring, Franz, Riedel, Gernot
Publicado no Behav Pharmacol (2015)

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer’s disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial...

Por Gauthier, Serge, Feldman, Howard H, Schneider, Lon S, Wilcock, Gordon K, Frisoni, Giovanni B, Hardlund, Jiri H, Moebius, Hans J, Bentham, Peter, Kook, Karin A, Wischik, Damon J, Schelter, Bjoern O, Davis, Charles S, Staff, Roger T, Bracoud, Luc, Shamsi, Kohkan, Storey, John M D, Harrington, Charles R, Wischik, Claude M
Publicado no Lancet (2016)

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome i...

Por Wilcock, Gordon K., Gauthier, Serge, Frisoni, Giovanni B., Jia, Jianping, Hardlund, Jiri H., Moebius, Hans J., Bentham, Peter, Kook, Karin A., Schelter, Bjoern O., Wischik, Damon J., Davis, Charles S., Staff, Roger T., Vuksanovic, Vesna, Ahearn, Trevor, Bracoud, Luc, Shamsi, Kohkan, Marek, Ken, Seibyl, John, Riedel, Gernot, Storey, John M.D., Harrington, Charles R., Wischik, Claude M.
Publicado no J Alzheimers Dis (2017)