Type 1 Diabetes Genetic Risk Score: a novel tool to discriminate monogenic and type 1 diabetes

Por Patel, K A, Oram, R A, Flanagan, S E, De Franco, E, Colclough, K, shepherd, M, Ellard, S, Weedon, M N, Hattersley, A T
Publicado no Diabetes (2016)

Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes

Por Edghill, E L, Khamis, A, Weedon, M N, Walker, M, Hitman, G A, McCarthy, M I, Owen, K R, Ellard, S, T Hattersley, A, Frayling, T M
Publicado em 2011

Improved genetic testing for monogenic diabetes using targeted next-generation sequencing

Por Ellard, S., Lango Allen, H., De Franco, E., Flanagan, S. E., Hysenaj, G., Colclough, K., Houghton, J. A. L., Shepherd, M., Hattersley, A. T., Weedon, M. N., Caswell, R.
Publicado em 2013

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes

Por Rafiq, S., Melzer, D., Weedon, M. N., Lango, H., Saxena, R., Scott, L. J., Palmer, C. N. A., Morris, A. D., McCarthy, M. I., Ferrucci, L., Hattersley, A. T., Zeggini, E., Frayling, T. M.
Publicado em 2008

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference

Por Rees, S. D., Islam, M., Hydrie, M. Z. I., Chaudhary, B., Bellary, S., Hashmi, S., O’Hare, J. P., Kumar, S., Sanghera, D. K., Chaturvedi, N., Barnett, A. H., Shera, A. S., Weedon, M. N., Basit, A., Frayling, T. M., Kelly, M. A., Jafar, T. H.
Publicado em 2011

A role for coding functional variants in HNF4A in Type 2 Diabetes susceptibility

Por Jafar-Mohammadi, B, Groves, C J, Gjesing, A P, Herrera, B M, Winckler, W, Stringham, H M, Morris, A P, Lauritzen, T, Doney, A S F, Morris, A D, Weedon, M N, Swift, A J, Kuusisto, J, Laakso, M, Altshuler, D, Hattersley, A T, Collins, F S, Boehnke, M, Hansen, T, Pedersen, O, Palmer, C N A, Frayling, T M, Gloyn, A L, McCarthy, M I
Publicado em 2010

Genetic association analysis of LARS2 with type 2 diabetes

Por Reiling, E., Jafar-Mohammadi, B., van ’t Riet, E., Weedon, M. N., van Vliet-Ostaptchouk, J. V., Hansen, T., Saxena, R., van Haeften, T. W., Arp, P. A., Das, S., Nijpels, G., Groenewoud, M. J., van Hove, E. C., Uitterlinden, A. G., Smit, J. W. A., Morris, A. D., Doney, A. S. F., Palmer, C. N. A., Guiducci, C., Hattersley, A. T., Frayling, T. M., Pedersen, O., Slagboom, P. E., Altshuler, D. M., Groop, L., Romijn, J. A., Maassen, J. A., Hofker, M. H., Dekker, J. M., McCarthy, M. I., ’t Hart, L. M.
Publicado em 2009