BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

Por Carrington, Emma M., Vikstrom, Ingela B., Light, Amanda, Sutherland, Robyn M., Londrigan, Sarah L., Mason, Kylie D., Huang, David C. S., Lew, Andrew M., Tarlinton, David M.
Publicado em 2010

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Por Vikström, Ingela B, Slomp, Anne, Carrington, Emma M, Moesbergen, Laura M, Chang, Catherine, Kelly, Gemma L, Glaser, Stefan P, Jansen, J H Marco, Leusen, Jeanette H W, Strasser, Andreas, Huang, David C S, Lew, Andrew M, Peperzak, Victor, Tarlinton, David M
Publicado no Cell Death Dis (2016)

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Por Carrington, Emma M, Zhan, Yifan, Brady, Jamie L, Zhang, Jian-Guo, Sutherland, Robyn M, Anstee, Natasha S, Schenk, Robyn L, Vikstrom, Ingela B, Delconte, Rebecca B, Segal, David, Huntington, Nicholas D, Bouillet, Philippe, Tarlinton, David M, Huang, David CS, Strasser, Andreas, Cory, Suzanne, Herold, Marco J, Lew, Andrew M
Publicado no Cell Death Differ (2017)

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

Por Carrington, Emma M., Zhang, Jian-Guo, Sutherland, Robyn M., Vikstrom, Ingela B., Brady, Jamie L., Soo, Priscilla, Vremec, David, Allison, Cody, Lee, Erinna F., Fairlie, W. Douglas, Bouillet, Philippe, Grabow, Stephanie, Ottina, Eleonora, Herold, Marco J., Pellegrini, Marc, Huang, David C. S., Tarlinton, David M., Strasser, Andreas, Lew, Andrew M., Zhan, Yifan
Publicado no Proc Natl Acad Sci U S A (2015)