Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo

door Ehmer, Ursula, Zmoos, Anne-Flore, Auerbach, Raymond K., Vaka, Dedeepya, Butte, Atul J., Kay, Mark A., Sage, Julien
Gepubliceerd in 2014

Whole exome and whole genome sequencing with dried blood spot DNA without whole genome amplification

door Bassaganyas, Laia, Freedman, George, Vaka, Dedeepya, Wan, Eunice, Lao, Richard, Chen, Flavia, Kvale, Mark, Currier, Robert J., Puck, Jennifer M., Kwok, Pui-Yan
Gepubliceerd in Hum Mutat (2017)

A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma

door Chen, Ron, Khatri, Purvesh, Mazur, Pawel K., Polin, Melanie, Zheng, Yanyan, Vaka, Dedeepya, Hoang, Chuong D., Shrager, Joseph, Xu, Yue, Vicent, Silvestre, Butte, Atul, Sweet-Cordero, E. Alejandro
Gepubliceerd in 2014

Tissue signals imprint ILC2 identity with anticipatory function

door Ricardo-Gonzalez, Roberto R., Van Dyken, Steven J., Schneider, Christoph, Lee, Jinwoo, Nussbaum, Jesse C., Liang, Hong-Erh, Vaka, Dedeepya, Eckalbar, Walter L., Molofsky, Ari B., Erle, David J., Locksley, Richard M.
Gepubliceerd in Nat Immunol (2018)

Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL6 in non-small cell lung cancer in vivo

door Vicent, Silvestre, Sayles, Leanne C., Vaka, Dedeepya, Khatri, Purvesh, Gevaert, Olivier, Chen, Ron, Zheng, Yanyan, Gillespie, Anna K., Clarke, Nicole, Xu, Yue, Shrager, Joseph, Hoang, Chuong D., Plevritis, Sylvia, Butte, Atul J., Sweet-Cordero, E. Alejandro
Gepubliceerd in 2012

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors

door Jahchan, Nadine S, Dudley, Joel T, Mazur, Pawel K, Flores, Natasha, Yang, Dian, Palmerton, Alec, Zmoos, Anne-Flore, Vaka, Dedeepya, Tran, Kim QT, Zhou, Margaret, Krasinska, Karolina, Riess, Jonathan W, Neal, Joel W, Khatri, Purvesh, Park, Kwon S, Butte, Atul J, Sage, Julien
Gepubliceerd in 2013

Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis

door Wong, Karen H.Y., Levy‐Sakin, Michal, Ma, Walfred, Gonzaludo, Nina, Mak, Angel C.Y., Vaka, Dedeepya, Poon, Annie, Chu, Catherine, Lao, Richard, Balamir, Melek, Grenville, Zoe, Wong, Nicolas, Kane, John P., Kwok, Pui‐Yan, Malloy, Mary J., Pullinger, Clive R.
Gepubliceerd in Mol Genet Genomic Med (2019)

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

door Zheng, Yanyan, de la Cruz, Cecile C., Sayles, Leanne C., Alleyne-Chin, Chris, Vaka, Dedeepya, Knaak, Tim D., Bigos, Marty, Xu, Yue, Hoang, Chuong D., Shrager, Joseph, Fehling, Hans Joerg, French, Dorothy, Forrest, William, Jiang, Zhaoshi, Jackson, Erica L., Sweet-Cordero, E. Alejandro
Gepubliceerd in 2013

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

door Marques Howarth, Michelle, Simpson, David, Ngok, Siu P., Nieves, Bethsaida, Chen, Ron, Siprashvili, Zurab, Vaka, Dedeepya, Breese, Marcus R., Crompton, Brian D., Alexe, Gabriela, Hawkins, Doug S., Jacobson, Damon, Brunner, Alayne L., West, Robert, Mora, Jaume, Stegmaier, Kimberly, Khavari, Paul, Sweet-Cordero, E. Alejandro
Gepubliceerd in J Clin Invest (2014)

Blimp1 induces transient metastatic heterogeneity in pancreatic cancer

door Chiou, Shin-Heng, Risca, Viviana I., Wang, Gordon X., Yang, Dian, Grüner, Barbara M., Kathiria, Arwa S., Ma, Rosanna K., Vaka, Dedeepya, Chu, Pauline, Kozak, Margaret, Castellini, Laura, Graves, Edward E., Kim, Grace E., Mourrain, Philippe, Koong, Albert C., Giaccia, Amato J., Winslow, Monte M.
Gepubliceerd in Cancer Discov (2017)

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

door Kareta, Michael S., Gorges, Laura L., Hafeez, Sana, Benayoun, Bérénice A., Marro, Samuele, Zmoos, Anne-Flore, Cecchini, Matthew J., Spacek, Damek, Batista, Luis F.Z., O’Brien, Megan, Ng, Yi-Han, Ang, Cheen Euong, Vaka, Dedeepya, Artandi, Steven E., Dick, Frederick A., Brunet, Anne, Sage, Julien, Wernig, Marius
Gepubliceerd in Cell Stem Cell (2014)

Identification and targeting of long-term tumor-propagating cells in small cell lung cancer

door Jahchan, Nadine S., Lim, Jing Shan, Bola, Becky, Morris, Karen, Seitz, Garrett, Tran, Kim Q., Xu, Lei, Trapani, Francesca, Morrow, Christopher J., Cristea, Sandra, Coles, Garry L., Yang, Dian, Vaka, Dedeepya, Kareta, Michael S., George, Julie, Mazur, Pawel K., Nguyen, Thuyen, Anderson, Wade C., Dylla, Scott J., Blackhall, Fiona, Peifer, Martin, Dive, Caroline, Sage, Julien
Gepubliceerd in Cell Rep (2016)

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

door Oh, Sekyung, Flynn, Ryan A., Floor, Stephen N., Purzner, James, Martin, Lance, Do, Brian T., Schubert, Simone, Vaka, Dedeepya, Morrissy, Sorana, Li, Yisu, Kool, Marcel, Hovestadt, Volker, Jones, David T.W., Northcott, Paul A., Risch, Thomas, Warnatz, Hans-Jörg, Yaspo, Marie-Laure, Adams, Christopher M., Leib, Ryan D., Breese, Marcus, Marra, Marco A., Malkin, David, Lichter, Peter, Doudna, Jennifer A., Pfister, Stefan M., Taylor, Michael D., Chang, Howard Y., Cho, Yoon-Jae
Gepubliceerd in Oncotarget (2016)

Comprehensive genomic profiles of small cell lung cancer

door George, Julie, Lim, Jing Shan, Jang, Se Jin, Cun, Yupeng, Ozretić, Luka, Kong, Gu, Leenders, Frauke, Lu, Xin, Fernández-Cuesta, Lynnette, Bosco, Graziella, Müller, Christian, Dahmen, Ilona, Jahchan, Nadine S., Park, Kwon-Sik, Yang, Dian, Karnezis, Anthony N., Vaka, Dedeepya, Torres, Angela, Wang, Maia Segura, Korbel, Jan O., Menon, Roopika, Chun, Sung-Min, Kim, Deokhoon, Wilkerson, Matt, Hayes, Neil, Engelmann, David, Pützer, Brigitte, Bos, Marc, Michels, Sebastian, Vlasic, Ignacija, Seidel, Danila, Pinther, Berit, Schaub, Philipp, Becker, Christian, Altmüller, Janine, Yokota, Jun, Kohno, Takashi, Iwakawa, Reika, Tsuta, Koji, Noguchi, Masayuki, Muley, Thomas, Hoffmann, Hans, Schnabel, Philipp A., Petersen, Iver, Chen, Yuan, Soltermann, Alex, Tischler, Verena, Choi, Chang-min, Kim, Yong-Hee, Massion, Pierre P., Zou, Yong, Jovanovic, Dragana, Kontic, Milica, Wright, Gavin M., Russell, Prudence A., Solomon, Benjamin, Koch, Ina, Lindner, Michael, Muscarella, Lucia A., la Torre, Annamaria, Field, John K., Jakopovic, Marko, Knezevic, Jelena, Castaños-Vélez, Esmeralda, Roz, Luca, Pastorino, Ugo, Brustugun, Odd-Terje, Lund-Iversen, Marius, Thunnissen, Erik, Köhler, Jens, Schuler, Martin, Botling, Johan, Sandelin, Martin, Sanchez-Cespedes, Montserrat, Salvesen, Helga B., Achter, Viktor, Lang, Ulrich, Bogus, Magdalena, Schneider, Peter M., Zander, Thomas, Ansén, Sascha, Hallek, Michael, Wolf, Jürgen, Vingron, Martin, Yatabe, Yasushi, Travis, William D., Nürnberg, Peter, Reinhardt, Christian, Perner, Sven, Heukamp, Lukas, Büttner, Reinhard, Haas, Stefan A., Brambilla, Elisabeth, Peifer, Martin, Sage, Julien, Thomas, Roman K.
Gepubliceerd in Nature (2015)