Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

por Serbulea, Vlad, Upchurch, Clint M., Schappe, Michael S., Voigt, Paxton, DeWeese, Dory E., Desai, Bimal N., Meher, Akshaya K., Leitinger, Norbert
Publicado no Proc Natl Acad Sci U S A (2018)

Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism

por Serbulea, Vlad, Upchurch, Clint M., Ahern, Katelyn W., Bories, Gael, Voigt, Paxton, DeWeese, Dory E., Meher, Akshaya K., Harris, Thurl E., Leitinger, Norbert
Publicado no Mol Metab (2017)

Mitochondrial Ca(2+) Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

por Seegren, Philip V., Downs, Taylor K., Stremska, Marta E., Harper, Logan R., Cao, Ruofan, Olson, Rachel J., Upchurch, Clint M., Doyle, Catherine A., Kennedy, Joel, Stipes, Eric L., Leitinger, Norbert, Periasamy, Ammasi, Desai, Bimal N.
Publicado no Cell Rep (2020)

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

por Kreutzberger, Alex J B, Kiessling, Volker, Doyle, Catherine A, Schenk, Noah, Upchurch, Clint M, Elmer-Dixon, Margaret, Ward, Amanda E, Preobraschenski, Julia, Hussein, Syed S, Tomaka, Weronika, Seelheim, Patrick, Kattan, Iman, Harris, Megan, Liang, Binyong, Kenworthy, Anne K, Desai, Bimal N, Leitinger, Norbert, Anantharam, Arun, Castle, J David, Tamm, Lukas K
Publicado no eLife (2020)

Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

por Senthivinayagam, Subramanian, Serbulea, Vlad, Upchurch, Clint M., Polanowska-Grabowska, Renata, Mendu, Suresh K., Sahu, Srabani, Jayaguru, Prathiba, Aylor, Kevin W., Chordia, Mahendra D., Steinberg, Limor, Oberholtzer, Nathaniel, Uchiyama, Seichii, Inada, Noriko, Lorenz, Ulrike M., Harris, Thurl E., Keller, Susanna R., Meher, Akshaya K., Kadl, Alexandra, Desai, Bimal N., Kundu, Bijoy K., Leitinger, Norbert
Publicado no Mol Metab (2020)